GTF2IRD2 anticorps

N° du produit ABIN7127095

L’anticorps Souris Monoclonal anti-GTF2IRD2 a été validé pour WB et FACS. Il convient pour détecter GTF2IRD2 dans des échantillons de Humain.

Aperçu rapide pour GTF2IRD2 anticorps (ABIN7127095)

Antigène: GTF2IRD2 (GTF2I Repeat Domain Containing 2 (GTF2IRD2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GTF2IRD2 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-GTF2IRD2 anticorps

Specificité: The TFII-I family contains two highly homologous 949 amino acid proteins, GTF2IRD2 (GTF2I repeat domain containing 2) and GTF2IRD2B (general transcription factor II-I repeat domain-containing protein 2B). Localizing to the nucleus, these proteins are ubiquitously expressed and contain two GTF2I- like repeats. Encoded by a gene mapping to human chromosome 7q11.23, GTF2IRD2 and GTF2IRD2B are located in the Williams-Beuren syndrome (WBS) critical region. The deletion of genes located within this region results in WBS, possibly due to the unequal crossing over of highly homologous low-copy repeat sequences that flank the deleted region. WBS is an autosomal dominant genetic condition that is characterized by physical, cognitive and behavioral traits including facial dysmorphology, vascular stenoses, growth deficiencies, dental anomalies and neurologic and musculoskeletal abnormalities.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant full-length human GTF2IRD2 protein

Isotype: IgG2a

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (1-2 μg/million cells), Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: HeLa or K562 cells.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur GTF2IRD2

Antigène: GTF2IRD2 (GTF2I Repeat Domain Containing 2 (GTF2IRD2))

Autre désignation: GTF2IRD2

Sujet: FP630, GTF2IRD2A, GTF2IRD2 alpha,GTF2IRD2
Cellular localisation: Nucleus.

Poids moléculaire: 107kDa

ID gène: 84163, 647039

UniProt: Q86UP8