INSM2 anticorps (AA 432-540)

N° du produit ABIN7127097

Cet anticorps Souris Monoclonal détecte spécifiquement INSM2 dans IHC (f). Il présente une réactivité envers Humain.

Aperçu rapide pour INSM2 anticorps (AA 432-540) (ABIN7127097)

Antigène: INSM2 (Insulinoma-Associated 2 (INSM2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp INSM2 est non-conjugé

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Détail du produit anti-INSM2 anticorps

Épitope: AA 432-540

Specificité: IA-6, also known as insulinoma-associated 2 or INSM2, is related to IA-1 (INSM1), a zinc-finger factor that is expressed in the developing nervous system. While the exact function of IA-6 is not known, other related insulinoma-associated proteins such as IA-2 are major autoantigens in type 1 diabetes. The homology exhibited by IA-6 to IA-1 has led to speculation that IA-6 may also play a role in the regulation of gene transcription. INSM2 may function as a growth suppressor or tumor suppressor in liver cells and in certain neurons.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant fragment of human INSM2 protein (around aa 432-540) (exact sequence is proprietary)

Isotype: IgG1

Information d'application

Indications d'application:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Human pancreas tissue.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur INSM2

Antigène: INSM2 (Insulinoma-Associated 2 (INSM2))

Autre désignation: INSM2

Sujet: IA1, Insulinoma associated protein 2 (IA2), Zinc finger protein IA6,Insulinoma Associated 2 / INSM2
Cellular localisation: Nuclear

Poids moléculaire: 58kDa

ID gène: 84684, 62813

UniProt: Q96T92