TSC22D1 anticorps

N° du produit ABIN7127120

Cet anticorps anti-TSC22D1 est un anticorps Souris Monoclonal détectant TSC22D1 dans WB, IF et FACS. Adapté pour Humain.

Aperçu rapide pour TSC22D1 anticorps (ABIN7127120)

Antigène: TSC22D1 (TSC22 Domain Family, Member 1 (TSC22D1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TSC22D1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-TSC22D1 anticorps

Specificité: Transforming growth factor i²-stimulated acts as a transcriptional regulator to modulate cell growth and differentiation and cell death. TSC-22 contains a leucine zipper domain as well as a nuclear export signal, resulting in cytoplasmic localization in living cells. However, concomitant with the induction of apoptosis, TSC-22 translocates from the cytoplasm to the nucleus and shows transcriptional regulatory activity. TSC-22 acts as a major downstream component in the TGFi² pathway and also the PPARi³ signaling pathway. The association of these two pathways with tumor suppression, and the significant downregulation of TSC-22 mRNA in various cancer types, such as brain and salivary gland tumors, imply an antiproliferative role for TSC-22.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant full-length human TSC22D1 protein

Isotype: IgG1

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Optimal dilution for a specific application should be determined.

Positive_Control: HeLa or HepG2 cells.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur TSC22D1

Antigène: TSC22D1 (TSC22 Domain Family, Member 1 (TSC22D1))

Autre désignation: TSC22D1

Sujet: Cerebral protein 2, Hucep2, KIAA1994, MGC17597, Regulatory protein TSC22, RP11 269C23.2, TGFB-stimulated clone 22 homolog, TGFB1I4, TGFbeta stimulated clone 22, Transcriptional regulator TSC 22, Transforming growth factor beta 1 induced transcript 4, Transforming growth factor beta 1 induced transcript 4 protein, TSC22D1,TSC22D1
Cellular localisation: Cytoplasm. Nucleus. Localized to nucleoplasm and nuclear bodies.

Poids moléculaire: 16kDa

ID gène: 8848, 436383

UniProt: Q15714