BPIFB1 anticorps

N° du produit ABIN7127157

Détail du produit anti-BPIFB1 anticorps

Antigène: BPIFB1 (BPI Fold Containing Family B, Member 1 (BPIFB1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BPIFB1 est non-conjugé

Application: Western Blotting (WB), ELISA, Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificité: The upper respiratory tract is the main place of entry for pathogens to invade the body, and early recognition of bacterial products in this region is crucial for host defense. Palate lung nasal epithelial clone PLUNC (or LUNX) is an airway specific secretory protein that is expressed in epithelial tissues and submucosal glands of the oral cavity and upper respiratory tract of humans, mice, rats and cows. PLUNC binds to lipopolysaccharide (LPS) in nasal lavage fluid (NLF) which points to its role in the inflammatory response of the upper airways after exposure to irritants. Decreased levels of PLUNC occur in the NLF of smokers and people who have been exposed to reactive epoxy chemicals, indicating that long-term exposure to airway irritants impairs the production of PLUNC in the upper respiratory tract. Abnormal expression of PLUNC may influence susceptibility to nasopharyngeal carcinoma in the Chinese population.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant full-length human BPIFB1 protein

Isotype: IgG

Information d'application

Indications d'application:

Known_Application: ELISA (For coating, order antibody without BSA), Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Human lung tissue. HeLa cells.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur BPIFB1

Antigène: BPIFB1 (BPI Fold Containing Family B, Member 1 (BPIFB1))

Autre désignation: BPIFB1 (BPIFB1 Produits)

Synonymes: anticorps C20orf114, anticorps LPLUNC1, anticorps Lplunc1, anticorps C13H20orf114, anticorps RGD1563047, anticorps BPI fold containing family B member 1, anticorps BPI fold containing family B, member 1, anticorps BPIFB1, anticorps Bpifb1

Sujet: BPI fold containing family B, member 1, Long palate, lung and nasal epithelium carcinoma associated protein 1 (Lplunc1), lung and nasal epithelium carcinoma-associated protein 1, VEMSGP, Von Ebner minor salivary gland protein,L-PLUNC
Cellular localisation: Secreted

Poids moléculaire: 25kDa

ID gène: 92747, 65551

UniProt: Q8TDL5