ZNF276 anticorps
Aperçu rapide pour ZNF276 anticorps (ABIN7127159)
Antigène
Voir toutes ZNF276 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF276 is a 614 amino acid protein containing five C2H2- type zinc fingers and one zinc finger associated (ZAD) domain. Due to a loss of heterozygosity at the chromosomal location of the gene encoding ZNF276 in sporadic breast cancers, the ZNF276 gene has been targeted as a possible breast cancer tumor suppressor. The FANCA gene, which encodes a DNA repair protein, is situated at the same chromosomal location as the ZNF276 gene, suggesting a possible involvement of ZNF276 in the progression of Fanconi anemia, an autosomal recessive disorder which is caused by mutations in the gene encoding FANCA. There are two isoforms of ZNF276 that exist as a result of an alternative splicing event.
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Réactivité croisée (Details)
- Human.
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Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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Immunogène
- Recombinant full-length human ZNF276 protein
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Isotype
- IgG2b
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Indications d'application
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Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or K562 cells.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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Date de péremption
- 24 months
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- ZNF276 (Zinc Finger Protein 276 (ZNF276))
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Autre désignation
- ZNF276
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Sujet
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AW048709, D8Ertd370e, D8Ertd377e, FLJ38685, FLJ77809, HGNC:23330, ZFP276, Zinc finger protein (C2H2 type) 276, Zinc finger protein 276, Zinc finger protein 276 homolog, Zinc finger protein 477, ZNF276, ZNF477,ZNF276 (Transcription Factor)
Cellular localisation: Nucleus. Nucleoplasm. -
Poids moléculaire
- 67kDa
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ID gène
- 92822, 290154
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UniProt
- Q8N554
Antigène
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