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ZNF276 anticorps

Cet anticorps anti-ZNF276 est un anticorps Souris Monoclonal détectant ZNF276 dans ELISA, IF, Coat, FACS et IP. Adapté pour Humain.
N° du produit ABIN7127159

Aperçu rapide pour ZNF276 anticorps (ABIN7127159)

Antigène

Voir toutes ZNF276 Anticorps
ZNF276 (Zinc Finger Protein 276 (ZNF276))

Reactivité

  • 19
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
Humain

Hôte

  • 18
  • 1
Souris

Clonalité

  • 19
Monoclonal

Conjugué

  • 14
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp ZNF276 est non-conjugé

Application

ELISA, Immunofluorescence (IF), Coating (Coat), Flow Cytometry (FACS), Immunoprecipitation (IP)
  • Specificité

    Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF276 is a 614 amino acid protein containing five C2H2- type zinc fingers and one zinc finger associated (ZAD) domain. Due to a loss of heterozygosity at the chromosomal location of the gene encoding ZNF276 in sporadic breast cancers, the ZNF276 gene has been targeted as a possible breast cancer tumor suppressor. The FANCA gene, which encodes a DNA repair protein, is situated at the same chromosomal location as the ZNF276 gene, suggesting a possible involvement of ZNF276 in the progression of Fanconi anemia, an autosomal recessive disorder which is caused by mutations in the gene encoding FANCA. There are two isoforms of ZNF276 that exist as a result of an alternative splicing event.

    Réactivité croisée (Details)

    Human.

    Purification

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    Immunogène

    Recombinant full-length human ZNF276 protein

    Isotype

    IgG2b
  • Indications d'application

    Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa or K562 cells.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    Agent conservateur

    Azide free

    Stock

    -20 °C,-80 °C

    Stockage commentaire

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    Date de péremption

    24 months
  • Antigène

    ZNF276 (Zinc Finger Protein 276 (ZNF276))

    Autre désignation

    ZNF276

    Sujet

    AW048709, D8Ertd370e, D8Ertd377e, FLJ38685, FLJ77809, HGNC:23330, ZFP276, Zinc finger protein (C2H2 type) 276, Zinc finger protein 276, Zinc finger protein 276 homolog, Zinc finger protein 477, ZNF276, ZNF477,ZNF276 (Transcription Factor)
    Cellular localisation: Nucleus. Nucleoplasm.

    Poids moléculaire

    67kDa

    ID gène

    92822, 290154

    UniProt

    Q8N554
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