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CD48 anticorps (AA 59-178)

Cet anticorps Souris Monoclonal détecte spécifiquement CD48 dans WB et IHC (f). Il présente une réactivité envers Humain.
N° du produit ABIN7127217

Aperçu rapide pour CD48 anticorps (AA 59-178) (ABIN7127217)

Antigène

Voir toutes CD48 Anticorps
CD48

Reactivité

  • 99
  • 67
  • 11
  • 6
  • 5
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
Humain

Hôte

  • 73
  • 39
  • 25
  • 19
  • 5
Souris

Clonalité

  • 125
  • 33
  • 3
Monoclonal

Conjugué

  • 68
  • 15
  • 14
  • 11
  • 9
  • 5
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp CD48 est non-conjugé

Application

  • 114
  • 52
  • 23
  • 23
  • 21
  • 20
  • 13
  • 9
  • 8
  • 6
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • Épitope

    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 59-178

    Specificité

    Reacts with human CD48, a 45 kDa glycosyl phophatidyl-inositol (GPI)-anchored cell surface protein. CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibroblasts, epithelium and endothelium. CD48 is one of marker for detecting the defects of GPI anchoring structure on the patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2.

    Réactivité croisée (Details)

    Human.

    Purification

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    Immunogène

    Recombinant fragment (around aa 59-178) of human CD48 protein (exact sequence is proprietary)

    Isotype

    IgG2
  • Indications d'application

    Known_Application: Western Blot (2-4 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Raji cells. Human lymph node or tonsil.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    Agent conservateur

    Azide free

    Stock

    -20 °C,-80 °C

    Stockage commentaire

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    Date de péremption

    24 months
  • Antigène

    CD48

    Autre désignation

    CD48

    Sujet

    B-cell activation marker, B-lymphocyte activation marker BLAST-1, BCM1 surface antigen, BLAST1, CD48 antigen (B cell membrane protein), Signaling lymphocytic activation molecule 2 (SLAMF2), SLAM family member 2,CD48 (Pan Leukocyte Marker)
    Cellular localisation: Cell Surface

    Poids moléculaire

    45kDa

    ID gène

    962, 243564

    UniProt

    P09326
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