RBM8A anticorps

N° du produit ABIN7127238

Détail du produit anti-RBM8A anticorps

Antigène: RBM8A (RNA Binding Motif Protein 8A (RBM8A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RBM8A est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Specificité: Y14 Antibody is a high quality monoclonal Y14 antibody (also designated Y14 antibody) suitable for the detection of the Y14 protein of mouse, rat, human and Xenopus laevis origin. Y14 Antibody (4C4) is available as both the non-conjugated anti-Y14 antibody form, as well as multiple conjugated forms of anti-Y14 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor conjugates. The exon junction complex (EJC) is a multiprotein complex that assembles approximately 20-24 nucleotides upstream of exon-exon junctions in pre-mRNAs. It is involved in mRNA export, cytoplasmic localization, and nonsense-mediated mRNA decay. Members of the EJC include Y14, Aly/REF, Magoh, RNPS1, SRm160, and DEK. Aly/REF, Magoh, and Y14, identified as RBM8 in mouse and rat, make up the core of the EJC, and these proteins remain stably bound to spliced mRNAs in the cytoplasm until they are translated. Therefore, Y14, Aly/REF, and Magoh have the ability to communicate to the cytoplasm the processing history of the mRNA, including the position of the removed introns. The gene encoding human Y14 encodes three transcripts. Y14 is a ubiquitously expressed protein. Although Y14 shuttles to the cytoplasm, it is predominantly detected in the nucleus and is co-localized with oskar mRNA at the posterior pole of the cell.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant full-length human RBM8A protein

Isotype: IgG1

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Optimal dilution for a specific application should be determined.

Positive_Control: HeLa or HepG2 cells.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur RBM8A

Antigène: RBM8A (RNA Binding Motif Protein 8A (RBM8A))

Autre désignation: RBM8A (RBM8A Produits)

Synonymes: anticorps BOV-1A, anticorps BOV-1B, anticorps BOV-1C, anticorps C1DELq21.1, anticorps DEL1q21.1, anticorps MDS014, anticorps RBM8, anticorps RBM8B, anticorps TAR, anticorps Y14, anticorps ZNRP, anticorps ZRNP1, anticorps 2310057C03Rik, anticorps AA673428, anticorps Rbm8, anticorps RBM8A, anticorps rbm8, anticorps rbm8a, anticorps rnp-5, anticorps fb34f03, anticorps wu:fb34f03, anticorps zgc:110525, anticorps rbm8-A, anticorps rbm8a-A, anticorps rbm8-B, anticorps RNA binding motif protein 8A, anticorps RNA binding motif protein 8a, anticorps RNA binding motif protein 8A S homeolog, anticorps RNA binding motif protein 8A L homeolog, anticorps RBM8A, anticorps Rbm8a, anticorps rbm8a, anticorps rbm8a.S, anticorps rbm8a.L

Sujet: Binder of OVCA1-1, BOV1A, BOV1B, BOV1C, HSPC114, MDS014, ZRNP1, Ribonucleoprotein RBM8A, RNA-binding protein 8A, RNA-binding protein Y14,Y14 / RBM8A
Cellular localisation: Nucleus. Nucleus speckle. Cytoplasm. Nucleocytoplasmic shuttling protein.

Poids moléculaire: 24kDa

ID gène: 9939, 728824

UniProt: Q9Y5S9