Recombinant GPX4 anticorps
Aperçu rapide pour Recombinant GPX4 anticorps (ABIN7127521)
Antigène
Voir toutes GPX4 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- GPX4 Recombinant Monoclonal Antibody
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Purification
- Affinity-chromatography
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Immunogène
- A synthesized peptide derived from human GPX4
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Isotype
- IgG
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Indications d'application
- IHC:1:50-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- GPX4 (Glutathione Peroxidase 4 (GPX4))
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Autre désignation
- GPX4
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Sujet
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Background: Protects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility. Could play a major role in protecting mammals from the toxicity of ingested lipid hydroperoxides. Essential for embryonic development. Protects from radiation and oxidative damage. Essential for maturation and survival of photoreceptor cells. Plays a role in a primary T cell response to viral and parasitic infection by protecting T cells from ferroptosis, a cell death resulting from an iron-dependent accumulation of lipid reactive oxygen species, and by supporting T cell expansion.
Aliases: Phospholipid hydroperoxide glutathione peroxidase (PHGPx) (EC 1.11.1.12) (Glutathione peroxidase 4) (GPx-4) (GSHPx-4), GPX4
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UniProt
- P36969
Antigène
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