Recombinant MLKL anticorps (pSer358)

N° du produit ABIN7127713

Cet anticorps anti-MLKL est un anticorps Lapin Monoclonal détectant MLKL dans ELISA et IHC. Adapté pour Humain.

Aperçu rapide pour Recombinant MLKL anticorps (pSer358) (ABIN7127713)

Antigène: MLKL (Mixed Lineage Kinase Domain-Like (MLKL))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp MLKL est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Clone: 4A6

Détail du produit anti-MLKL anticorps

Épitope: pSer358

Réactivité croisée: Humain

Purification: Affinity-chromatography

Immunogène: A synthesized peptide derived from human Phospho-MLKL (S358)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MLKL

Antigène: MLKL (Mixed Lineage Kinase Domain-Like (MLKL))

Autre désignation: MLKL

Sujet:

Background: Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.

Aliases: Mixed lineage kinase domain-like protein, hMLKL, MLKL

UniProt: Q8NB16