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Recombinant SSTR2 anticorps

SSTR2 Reactivité: Humain IHC, ELISA Hôte: Lapin Monoclonal 1C3 unconjugated Recombinant Antibody
N° du produit ABIN7127820
  • Antigène Voir toutes SSTR2 Anticorps
    SSTR2 (Somatostatin Receptor 2 (SSTR2))
    Type d'anticorp
    Recombinant Antibody
    Reactivité
    • 44
    • 27
    • 26
    • 10
    • 9
    • 9
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 3
    • 3
    • 2
    • 1
    Humain
    Hôte
    • 41
    • 4
    Lapin
    Clonalité
    • 41
    • 3
    • 1
    Monoclonal
    Conjugué
    • 34
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SSTR2 est non-conjugé
    Application
    • 21
    • 13
    • 12
    • 10
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA
     Réactivité croisée
    Humain
    Purification
    Affinity-chromatography
    Immunogène
    A synthesized peptide derived from human Somatostatin Receptor 2
    Clone
    1C3
    Isotype
    IgG
    Top Product
    Discover our top product SSTR2 Anticorps primaire
  • Indications d'application
    Recommended dilution: IHC:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    SSTR2 (Somatostatin Receptor 2 (SSTR2))
    Autre désignation
    SSTR2 (SSTR2 Produits)
    Synonymes
    anticorps Smstr2, anticorps SSTR-2, anticorps Smstr-2, anticorps sst2, anticorps SS2R, anticorps SSTR2, anticorps MGC80373, anticorps somatostatin receptor 2, anticorps somatostatin receptor 2 L homeolog, anticorps SSTR2, anticorps Sstr2, anticorps sstr2.L
    Sujet

    Background: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

    Aliases: Somatostatin receptor type 2 (SS-2-R) (SS2-R) (SS2R) (SRIF-1), SSTR2

    UniProt
    P30874
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