Recombinant TACC3 anticorps
Aperçu rapide pour Recombinant TACC3 anticorps (ABIN7127834)
Antigène
Voir toutes TACC3 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Réactivité croisée
- Humain
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Purification
- Affinity-chromatography
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Immunogène
- A synthesized peptide derived from human TACC3
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Isotype
- IgG
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Indications d'application
- Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TACC3 (Transforming, Acidic Coiled-Coil Containing Protein 3 (TACC3))
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Autre désignation
- TACC3
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Sujet
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Background: Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity). Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension (PubMed:21297582, PubMed:23532825). May be involved in the control of cell growth and differentiation. May contribute to cancer (PubMed:14767476).
Aliases: Transforming acidic coiled-coil-containing protein 3 (ERIC-1), TACC3, ERIC1
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UniProt
- Q9Y6A5
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Pathways
- Maintenance of Protein Location
Antigène
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