Recombinant TXN anticorps

N° du produit ABIN7127856

Détail du produit anti-TXN anticorps

Antigène: TXN (Thioredoxin (TXN))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp TXN est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée: Humain, Rat

Purification: Affinity-chromatography

Immunogène: A synthesized peptide derived from human TRX1

Clone: 3G7

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TXN

Antigène: TXN (Thioredoxin (TXN))

Autre désignation: TXN (TXN Produits)

Synonymes: anticorps TRDX, anticorps TRX, anticorps TRX1, anticorps ADF, anticorps AW550880, anticorps Trx1, anticorps Txn, anticorps trx, anticorps TXN, anticorps SCM1.18, anticorps trxA3, anticorps thioredoxin, anticorps TR-1, anticorps Trx-1, anticorps thioredoxin, anticorps thioredoxin 1, anticorps thioredoxin L homeolog, anticorps similar to 44RRORF109c hypothetical protein; similar to bacterial thioredoxin (SwissProt P06544), anticorps thioredoxin pseudogene, anticorps cytosolic thioredoxin Trx1, anticorps TXN, anticorps Txn1, anticorps txn.L, anticorps txn, anticorps trx, anticorps SCO0885, anticorps PHG25ORF099c, anticorps LOC100349046, anticorps Txn, anticorps trx1

Sujet:

Background: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.

Aliases: Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP), TXN, TRDX TRX TRX1

UniProt: P10599

Pathways: Carbohydrate Homeostasis, Cell RedoxHomeostasis