PCP4 anticorps

N° du produit ABIN7130557

Détail du produit anti-PCP4 anticorps

Antigène: PCP4 (Purkinje Cell Protein 4 (PCP4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCP4 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Réactivité croisée: Humain, Souris, Rat

Purification: Antigen affinity purification

Immunogène: Fusion protein of Human PCP4

Isotype: IgG

Information d'application

Indications d'application: ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:5-1:20,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PCP4

Antigène: PCP4 (Purkinje Cell Protein 4 (PCP4))

Autre désignation: PCP4 (PCP4 Produits)

Synonymes: anticorps PEP-19, anticorps P16Rimb19, anticorps Pcp-4, anticorps Pep19, anticorps PEPZ19, anticorps pep-19, anticorps Purkinje cell protein 4, anticorps PCP4, anticorps Pcp4

Sujet:

Background: PCP-4 (Purkinje cell protein 4), also known as PEP-19, is a calmodulin (CaM) regulatory protein that is highly expressed in neuronal cells. Through its IQ motif, PCP-4 mediates both the calcium-dependent binding properties of CaM and the rates of association and dissociation of calcium from the C-terminal domain of CaM. The IQ motif contains a serine residue which can be phosphorylated by all isoforms of protein kinase C (PKC). PCP-4 is implicated in uterine leiomyomas, as well as in neurodegenerative disorders such as Alzheimer's disease and Huntington's disease. Additionally, overexpression of PCP-4 is thought to play a role in cerebellar hypoplasia, a key feature of Down syndrome.

Aliases: Brain specific antigen PCP 4 antibody, Brain specific polypeptide PEP 19 antibody, Brain specific polypeptide PEP19 antibody, Brain-specific antigen PCP-4 antibody, Brain-specific polypeptide PEP-19 antibody, OTTHUMP00000109191 antibody, Pcp4 antibody, PCP4_HUMAN antibody, PEP19 antibody, Purkinje cell protein 4 antibody

UniProt: P48539