PRCP anticorps

N° du produit ABIN7130695

Détail du produit anti-PRCP anticorps

Antigène: PRCP (Prolylcarboxypeptidase (PRCP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRCP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Réactivité croisée: Humain, Souris

Purification: Antigen affinity purification

Immunogène: Fusion protein of Human PRCP

Isotype: IgG

Information d'application

Indications d'application: ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PRCP

Antigène: PRCP (Prolylcarboxypeptidase (PRCP))

Autre désignation: PRCP (PRCP Produits)

Synonymes: anticorps OI13, anticorps PCOLC, anticorps PCP, anticorps PCP2, anticorps TLD, anticorps humpcp, anticorps MGC145178, anticorps 2510048K03Rik, anticorps 2610104A14Rik, anticorps AI451719, anticorps HUMPCP, anticorps zgc:91816, anticorps bone morphogenetic protein 1, anticorps prolylcarboxypeptidase, anticorps lysosomal Pro-X carboxypeptidase, anticorps prolylcarboxypeptidase (angiotensinase C), anticorps BMP1, anticorps prcp, anticorps LOC5579822, anticorps CpipJ_CPIJ006123, anticorps CpipJ_CPIJ006124, anticorps Prcp, anticorps PRCP

Sujet:

Background: The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH , but the enzyme activity is retained with some substrates at neutral pH . This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Aliases: Angiotensinase C antibody, HUMPCP antibody, Lysosomal carboxypeptidase C antibody, Lysosomal Pro X carboxypeptidase antibody, Lysosomal Pro-X carboxypeptidase antibody, MGC2202 antibody, PCP antibody, PCP_HUMAN antibody, PRCP antibody, Proline carboxypeptidase antibody, Prolylcarboxypeptidase (angiotensinase C) antibody, Prolylcarboxypeptidase antibody, prolylcarboxypeptidase isoform 1 preproprotein antibody

UniProt: P42785