DAB1 anticorps

N° du produit ABIN7138126

Cet anticorps anti-DAB1 Polyclonal Lapin (ABIN7138126) détecte spécifiquement DAB1 dans ELISA et IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour DAB1 anticorps (ABIN7138126)

Antigène: DAB1 (Disabled Homolog 1 (Drosophila) (DAB1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DAB1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-DAB1 anticorps

Fonction: DAB1 (Ab-232) Antibody

Réactivité croisée: Souris, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogène: Peptide sequence around aa.230~234 (G-V-Y-D-V) derived from Human Dab1.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur DAB1

Antigène: DAB1 (Disabled Homolog 1 (Drosophila) (DAB1))

Autre désignation: DAB1

Sujet:

Background: The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.

Kelian Chen, et,al. (2003) J. Cell Sci , 117: 4527 - 4536.
Vera Strasser, et,al. (2004) Mol. Cell. Biol , 24: 1378 - 1386.
Izhar Ben-Shlomo, et,al. (2003) Sci. STKE , 2003: 9.
H. M. Kim, et,al. (2002) PNAS , 99: 4020.

Aliases: Dab 1 antibody, Dab reelin signal transducer 1 antibody, Dab, reelin signal transducer, homolog 1 (Drosophila) antibody, Dab1 antibody, DAB1_HUMAN antibody, Disabled homolog 1 antibody, Disabled homolog 1 Drosophila antibody, Scm antibody, Scr antibody, Scrambler antibody, Yot antibody, Yotari antibody

UniProt: O75553