HDAC7 anticorps (pSer155)

N° du produit ABIN7138439

Cet anticorps Lapin Polyclonal détecte spécifiquement HDAC7 dans WB et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour HDAC7 anticorps (pSer155) (ABIN7138439)

Antigène: HDAC7 (Histone Deacetylase 7 (HDAC7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC7 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-HDAC7 anticorps

Épitope: pSer155

Réactivité croisée: Humain, Souris

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of Serine 155(T-V-S(p)-E-P) derived from Human HDAC7A.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:1000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur HDAC7

Antigène: HDAC7 (Histone Deacetylase 7 (HDAC7))

Autre désignation: HDAC7

Sujet:

Background:

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Walsh M.J., Submitted (FEB-2000).
Zelent A., Submitted (MAY-2003).
Sugano S., Nat. Genet. 36:40-45(2004)

Aliases: DKFZP586J0917 antibody, FLJ99588 antibody, HD 7a antibody, HD7 antibody, HD7a antibody, HDAC 7 antibody, HDAC 7A antibody, Hdac7 antibody, HDAC7_HUMAN antibody, HDAC7A antibody, Histone deacetylase 7 antibody, Histone deacetylase 7A antibody, OTTHUMP00000202813 antibody, OTTHUMP00000202814 antibody

UniProt: Q8WUI4

Pathways: Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development