CCR5 anticorps (pSer349)

N° du produit ABIN7138569

L’anticorps Lapin Polyclonal anti-CCR5 a été validé pour WB et ELISA. Il convient pour détecter CCR5 dans des échantillons de Humain.

Aperçu rapide pour CCR5 anticorps (pSer349) (ABIN7138569)

Antigène: CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCR5 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CCR5 anticorps

Épitope: pSer349

Fonction: Phospho-CCR5 (Ser349) Antibody

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of Serine 349 (E-I-S(p)-V-G) derived from Human CCR5.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CCR5

Antigène: CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

Autre désignation: CCR5

Sujet:

Background:

Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.

Martin Oppermann, J. Biol. Chem., Mar 1999, 274: 8875.
Beatrix Pollok-Kopp, J. Biol. Chem., Jan 2003, 278: 2190 - 2198.
Ramtin Rahbar, J. Virol., Jul 2006, 80: 7245 - 7259.
H Olbrich, J. Leukoc. Biol., Mar 1999, 65: 281.

Aliases: AM4 7 antibody, C C chemokine receptor type 5 antibody, C C CKR 5 antibody, C-C chemokine receptor type 5 antibody, C-C CKR-5 antibody, C-C motif chemokine receptor 5 A159A antibody, CC Chemokine Receptor 5 antibody, CC Chemokine Receptor Type 5 antibody, CC CKR 5 antibody, CC-CKR-5 antibody, CCCKR 5 antibody, CCCKR5 antibody, CCR 5 antibody, CCR-5 antibody, CCR5 antibody, CCR5 chemokine (C C motif) receptor 5 antibody, CCR5_HUMAN antibody, CD 195 antibody, CD195 antibody, CD195 Antigen antibody, Chemokine C C motif receptor 5 antibody, Chemokine receptor CCR5 antibody, CHEMR13 antibody, CKR 5 antibody, CKR5 antibody, CMKBR 5 antibody, CMKBR5 antibody, FLJ78003 antibody, HIV 1 Fusion Coreceptor antibody, HIV-1 fusion coreceptor antibody, HIV1 fusion coreceptor antibody, IDDM22 antibody, MIP-1 alpha receptor antibody

UniProt: P51681

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size