Ataxin 1 anticorps (pSer776)

N° du produit ABIN7138699

Cet anticorps anti-Ataxin 1 est un anticorps Lapin Polyclonal détectant Ataxin 1 dans WB et ELISA. Adapté pour Humain.

Aperçu rapide pour Ataxin 1 anticorps (pSer776) (ABIN7138699)

Antigène: Ataxin 1 (ATXN1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ataxin 1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Ataxin 1 anticorps

Épitope: pSer776

Fonction: Phospho-ATXN1 (Ser776) Antibody

Réactivité croisée: Souris

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of Serine 776(R-W-S(p)-A-P) derived from Human Ataxin 1.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Ataxin 1

Antigène: Ataxin 1 (ATXN1)

Autre désignation: ATXN1

Sujet:

Background: Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. The expansion of the polyglutamine tract may alter this function.

Aliases: alternative ataxin1 antibody, Ataxin-1 antibody, ATX1 antibody, ATX1_HUMAN antibody, Atxn1 antibody, D6S504E antibody, OTTHUMP00000016065 antibody, SCA1 antibody, Spinocerebellar ataxia type 1 protein antibody

UniProt: P54253

Pathways: Synaptic Membrane