HNRNPD/AUF1 anticorps (pSer83)

N° du produit ABIN7138711

Cet anticorps anti-HNRNPD/AUF1 est un anticorps Lapin Polyclonal détectant HNRNPD/AUF1 dans WB, IHC, ELISA et IF. Adapté pour Humain.

Aperçu rapide pour HNRNPD/AUF1 anticorps (pSer83) (ABIN7138711)

Antigène: HNRNPD/AUF1 (HNRNPD) (Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HNRNPD/AUF1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-HNRNPD/AUF1 anticorps

Épitope: pSer83

Fonction: Phospho-HNRNPD (Ser83) Antibody

Réactivité croisée: Souris

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of Serine 83(N-S-S(p)-P-R) derived from Human hnRPD .

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur HNRNPD/AUF1

Antigène: HNRNPD/AUF1 (HNRNPD) (Heterogeneous Nuclear Ribonucleoprotein D (HNRNPD))

Autre désignation: HNRNPD

Sujet:

Background:

Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Also binds to double- and single-stranded DNA sequences in a specific manner and functions a transcription factor. Each of the RNA-binding domains specifically can bind solely to a single-stranded non-monotonous 5'-UUAG-3' sequence and also weaker to the single-stranded 5'-TTAGGG-3' telomeric DNA repeat. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats.

Kajita Y., J. Biol. Chem. 270:22167-22175(1995).
Dempsey L.A., Genomics 49:378-384(1998).
Tolnay M., Biochem. J. 338:417-425(1999).
Grosset C., Cell 103:29-40(2000)

Aliases: ARE binding protein AUFI type A antibody, AU-rich element RNA-binding protein 1 antibody, AUF antibody, AUF1 antibody, AUF1A antibody, Heterogeneous nuclear ribonucleoprotein D0 antibody, hnRNP D antibody, hnRNP D0 antibody, Hnrnpd antibody, hnRNPD0 antibody, HNRPD antibody, HNRPD_HUMAN antibody, P37 antibody

UniProt: Q14103