PLD1 anticorps (pThr147)
Aperçu rapide pour PLD1 anticorps (pThr147) (ABIN7138779)
Antigène
Voir toutes PLD1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pThr147
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Fonction
- Phospho-PLD1 (Thr147) Antibody
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Réactivité croisée
- Souris, Rat
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Purification
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
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Immunogène
- Peptide sequence around phosphorylation site of threonine 147(R-H-T(p)-F-R) derived from Human PLD1.
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PLD1 (Phospholipase D1 (PLD1))
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Autre désignation
- PLD1
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Sujet
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Background:
Phosphatidylcholine (PC)-specific phospholipases D (PLDs, EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. A range of agonists acting through G protein-coupled receptors and receptor tyrosine kinases stimulate this hydrolysis. PC-specific PLD activity has been implicated in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis.
Hammond S.M., J. Biol. Chem. 272:3860-3868(1997) [PubMed: 9013646].
Steed P.M., FASEB J. 12:1309-1317(1998) [PubMed: 9761774].
Lopez I., J. Biol. Chem. 273:12846-12852(1998) [PubMed: 9582313].Aliases: Choline phosphatase 1 antibody, hPLD1 antibody, Phosphatidylcholine-hydrolyzing phospholipase D1 antibody, Phospholipase D1 antibody, PLD 1 antibody, PLD1 antibody, PLD1_HUMAN antibody
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UniProt
- Q13393
Antigène
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