Calmodulin 1 anticorps (pSer81, pThr79)

N° du produit ABIN7138901

Cet anticorps Lapin Polyclonal détecte spécifiquement Calmodulin 1 dans WB et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour Calmodulin 1 anticorps (pSer81, pThr79) (ABIN7138901)

Antigène: Calmodulin 1 (Calm1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Calmodulin 1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Calmodulin 1 anticorps

Épitope: pSer81, pThr79

Fonction: Phospho-CALM1 (Thr79/Ser81) Antibody

Réactivité croisée: Souris, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of threonine79/serine81(K-D-T(p)-D-S(p)-E-E) derived from Human Calmodulin .

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Calmodulin 1

Antigène: Calmodulin 1 (Calm1)

Autre désignation: CALM1

Sujet:

Background:

Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca2+. Among the enzymes to be stimulated by the calmodulin-Ca2+ complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis.

Allen D, Fakler B, Maylie J, Adelman JP (2007) J Neurosci 27, 2369-76
Arrigoni G, et al. (2004) Biochemistry 43, 12788-98
Greif DM, Sacks DB, Michel T (2004) Proc Natl Acad Sci U S A 101, 1165-70

Aliases: CALM, CALM1, CALM2, CALM3, CAM

UniProt: P62158

Pathways: cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Phototransduction, BCR Signaling