MYL9 anticorps (pTyr118)

N° du produit ABIN7138917

L’anticorps Lapin Polyclonal anti-MYL9 a été validé pour WB, ELISA et IF. Il convient pour détecter MYL9 dans des échantillons de Humain.

Aperçu rapide pour MYL9 anticorps (pTyr118) (ABIN7138917)

Antigène: MYL9 (Myosin Regulatory Light Polypeptide 9 (MYL9))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYL9 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-MYL9 anticorps

Épitope: pTyr118

Fonction: Phospho-MYL9 (Tyr118) Antibody

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of tyrosine 118 (A-D-Y(p)-V-R) derived from Human MLC2.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MYL9

Antigène: MYL9 (Myosin Regulatory Light Polypeptide 9 (MYL9))

Autre désignation: MYL9

Sujet:

Background:  Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion. 1) Xia, Y. et al. c-Jun downregulation by HDAC3-dependent transcriptional repression promotes osmotic stress-induced cell apoptosis. Mol. Cell 25, 219–232 (2007).2)Vander Heiden, M. G. et al. Evidence for an alternative glycolytic pathway in rapidly proliferating cells. Science 329, 1492–1499 (2010).3) Fang, D. et al. Phosphorylation of beta-catenin by AKT promotes beta-catenin transcriptional activity. J. Biol. Chem. 282, 11221–11229 (2007).

Aliases: 20 kDa myosin light chain antibody; Human 20kDa myosin light chain (MLC2) mRNA complete cds antibody; LC20 antibody; MGC3505 antibody; MLC 2 antibody; MLC-2C antibody; MLC2 antibody; MLY 9 antibody; MRLC1 antibody; MYL9 antibody; MYL9_HUMAN antibody; Myosin light chain 9 regulatory antibody; Myosin light polypeptide 9 regulatory antibody; myosin regulatory light chain 1 antibody; Myosin regulatory light chain 2 antibody; Myosin regulatory light chain 2 smooth muscle isoform antibody; Myosin regulatory light chain 9 antibody; Myosin regulatory light chain MRLC1 antibody; Myosin regulatory light polypeptide 9 antibody; Myosin RLC antibody; Myosin vascular smooth muscle light chain 2 antibody; MYRL2 antibody; OTTHUMP00000030857 antibody; smooth muscle isoform antibody

UniProt: P24844