DOK2 anticorps (pTyr299)

N° du produit ABIN7138971

L’anticorps anti-DOK2 Polyclonal produit chez le Lapin a été validé pour WB, ELISA, IHC et IF. Il convient pour la détection de DOK2 dans des échantillons provenant de Humain. }

Aperçu rapide pour DOK2 anticorps (pTyr299) (ABIN7138971)

Antigène: DOK2

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DOK2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-DOK2 anticorps

Épitope: pTyr299

Fonction: Phospho-DOK2 (Tyr299) Antibody

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of tyrosine 299 (G-E-Y(p)-A-V) derived from Human p56Dok-2.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur DOK2

Antigène: DOK2

Autre désignation: DOK2

Sujet:

Background:

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation

Feng Cong, et,al. (1999) Mol. Cell. Biol , 19: 8314 - 8325.
Serge Lemay, et,al. (2000) Mol. Cell. Biol , 20: 2743 - 2754.
Ute Schaeper, et,al.(2000) J. Cell Biol , 149: 1419.
Miyuki Honma, et,al. (2006) Genes Cells, 11: 143 - 151.

Aliases: Docking protein 2 56 kDa antibody, Docking protein 2 antibody, DOK 2 antibody, DOK R antibody, DOK2 antibody, DOK2_HUMAN antibody, Downstream of tyrosine kinase 2 antibody, OTTHUMP00000161710 antibody, OTTHUMP00000224923 antibody, p56(dok 2) antibody, p56(dok-2) antibody, p56dok 2 antibody, p56DOK antibody, p56dok2 antibody

UniProt: O60496