INPP5F anticorps (AA 187-204) (Biotin)

N° du produit ABIN7140041

Cet anticorps Lapin Polyclonal détecte spécifiquement INPP5F dans ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour INPP5F anticorps (AA 187-204) (Biotin) (ABIN7140041)

Antigène: INPP5F (Inositol Polyphosphate-5-Phosphatase F (INPP5F))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp INPP5F est conjugé à/à la Biotin

Application: ELISA

Détail du produit anti-INPP5F anticorps (Biotin)

Épitope: AA 187-204

Fonction: INPP5F Antibody, Biotin conjugated

Purification: Protein G purified

Pureté: >95 %

Immunogène: Peptide sequence from Human Phosphatidylinositide phosphatase SAC2 protein (187-204AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur INPP5F

Antigène: INPP5F (Inositol Polyphosphate-5-Phosphatase F (INPP5F))

Autre désignation: INPP5F

Sujet:

Background: Inositol 4-phosphatase which mainly acts on phosphatidylinositol 4-phosphate. May be functionally linked to OCRL, which converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol, for a sequential dephosphorylation of phosphatidylinositol 4,5-bisphosphate at the 5 and 4 position of inositol, thus playing an important role in the endocytic recycling (PubMed:25869669). Regulator of TF:TFRC and integrins recycling pathway, is also involved in cell migration mechanisms (PubMed:25869669). Modulates AKT/GSK3B pathway by decreasing AKT and GSK3B phosphorylation (PubMed:17322895). Negatively regulates STAT3 signaling pathway through inhibition of STAT3 phosphorylation and translocation to the nucleus (PubMed:25476455). Functionally important modulator of cardiac myocyte size and of the cardiac response to stress (By similarity). May play a role as negative regulator of axon regeneration after central nervous system injuries (By similarity).

Aliases: INPP5F antibody, KIAA0966 antibody, SAC2 antibody, MSTP007 antibody, MSTP047 antibody, Phosphatidylinositide phosphatase SAC2 antibody, EC 3.1.3.25 antibody, Inositol polyphosphate 5-phosphatase F antibody, Sac domain-containing inositol phosphatase 2 antibody, Sac domain-containing phosphoinositide 4-phosphatase 2 antibody, hSAC2 antibody

UniProt: Q9Y2H2