LRP1 anticorps (AA 3924-3942)

N° du produit ABIN7140070

Cet anticorps anti-LRP1 est un anticorps Lapin Polyclonal détectant LRP1 dans IHC, ELISA et IF. Adapté pour Humain.

Aperçu rapide pour LRP1 anticorps (AA 3924-3942) (ABIN7140070)

Antigène: LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRP1 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-LRP1 anticorps

Épitope: AA 3924-3942

Fonction: LRP1 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Peptide sequence from Human Prolow-density lipoprotein receptor-related protein 1 protein (3924-3942AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur LRP1

Antigène: LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))

Autre désignation: LRP1

Sujet:

Background: Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission (PubMed:11907044, PubMed:12888553, PubMed:12713657). Acts as an alpha-2-macroglobulin receptor (PubMed:26142438).

Aliases: A2MR antibody, Alpha 2 macroglobulin receptor antibody, alpha 2MR antibody, Alpha-2-macroglobulin receptor antibody, APOER antibody, Apolipoprotein E receptor antibody, APR antibody, CD 91 antibody, CD91 antibody, CD91 antigen antibody, IGFBP3R antibody, LDL receptor related protein 1 antibody, Low density lipoprotein receptor related protein 1 antibody, Low density lipoprotein related protein 1 antibody, Low-density lipoprotein receptor-related protein 1 intracellular domain antibody, LRP 1 antibody, LRP 515 antibody, LRP 85 antibody, LRP antibody, LRP ICD antibody, LRP-1 antibody, LRP-515 antibody, LRP-85 antibody, Lrp1 antibody, LRP1 protein antibody, LRP1_HUMAN antibody, LRP1A antibody, LRP515 antibody, LRP85 antibody, LRPICD antibody, MGC88725 antibody, Prolow density lipoprotein receptor related protein 1 antibody, TbetaR V/LRP 1/IGFBP 3 receptor antibody, TbetaRV/LRP1/IGFBP3 receptor antibody, TGFBR 5 antibody, TGFBR5 antibody, Type V tgf beta receptor antibody

UniProt: Q07954

Pathways: Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling