Znf423 anticorps (AA 39-57)
Aperçu rapide pour Znf423 anticorps (AA 39-57) (ABIN7140239)
Antigène
Voir toutes Znf423 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 39-57
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Fonction
- ZNF423 Antibody
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Purification
- Antigen Affinity Purified
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Immunogène
- Peptide sequence from Human Zinc finger protein 423 protein (39-57AA)
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Znf423 (Zinc Finger Protein 423 (Znf423))
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Autre désignation
- ZNF423
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Sujet
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Background: Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation, this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Controls proliferation and differentiation of neural precursors in cerebellar vermis formation.
Aliases: Early B cell factor associated zinc finger protein antibody, Ebfaz antibody, hOAZ antibody, JBTS19 antibody, KIAA0760 antibody, NPHP14 antibody, Nur12 antibody, OAZ antibody, OLF 1/EBF associated zinc finger antibody, OLF1/EBF associated zinc finger protein antibody, Olf1/EBF-associated zinc finger protein antibody, Roaz antibody, Smad and Olf interacting zinc finger protein antibody, Smad- and Olf-interacting zinc finger protein antibody, Zfp104 antibody, ZFP423 antibody, zinc finger protein 423, mouse, homolog of antibody, Zinc finger protein 423 antibody, ZN423_HUMAN antibody, ZNF423 antibody, ZNF423 zinc finger protein 423 antibody
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UniProt
- Q2M1K9
Antigène
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