CBR1 anticorps
Aperçu rapide pour CBR1 anticorps (ABIN7140302)
Antigène
Voir toutes CBR1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- CBR1 Monoclonal Antibody
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Purification
- Affinity purified
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Immunogène
- Purified recombinant human CBR1 protein fragments expressed in E.coli
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Isotype
- IgG1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS( pH 7.4)containing with 0.2 % sodium azide,50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CBR1 (Carbonyl Reductase 1 (CBR1))
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Autre désignation
- CBR1
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Sujet
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Background: NADPH-dependent reductase with broad substrate specificity.Catalyzes the reduction of a wide variety of carbonyl compounds including quinones,prostaglandins, menadione,plus various xenobiotics.Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha.Can bind glutathione,which explains its higher affinity for glutathione-conjugated substrates.Catalyzes the reduction of S-nitrosoglutathione.
Aliases: 15 hydroxyprostaglandin dehydrogenase [NADP+], 15-hydroxyprostaglandin dehydrogenase [NADP+], Carbonyl reductase [NADPH] 1, Carbonyl Reductase 1, CBR 1, CBR1, CBR1_HUMAN, CRN, NADPH dependent carbonyl reductase 1, NADPH-dependent carbonyl reductase 1,
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UniProt
- P16152
Antigène
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