WDR77 anticorps

N° du produit ABIN7140359

Cet anticorps Souris Monoclonal détecte spécifiquement WDR77 dans WB, ELISA et ICC. Il présente une réactivité envers Humain.

Aperçu rapide pour WDR77 anticorps (ABIN7140359)

Antigène: WDR77 (WD Repeat Domain 77 (WDR77))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp WDR77 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Détail du produit anti-WDR77 anticorps

Fonction: WDR77 Monoclonal Antibody

Réactivité croisée: Souris, Rat

Purification: Affinity purified

Immunogène: Purified recombinant human WDR77 protein fragments expressed in E.coli.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS( pH 7.4) containing with 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur WDR77

Antigène: WDR77 (WD Repeat Domain 77 (WDR77))

Autre désignation: WDR77

Sujet:

Background: Non-catalytic component of the 20S PRMT5-containing methyltransferase complex,which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones.This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles.Might play a role in transcription regulation.The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4),methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.

Aliases: 2610312E17Rik, Androgen receptor cofactor p44, C79984, HKMT1069, MEP 50, MEP-50, MEP50, MEP50_HUMAN, Methylosome protein 50, MGC2722, Nbla10071, p44, p44/Mep50, RGD1310479, RP11 552M11.3, WD repeat containing protein 77, WD repeat domain 77,

UniProt: Q9BQA1

Pathways: Ribonucleoprotein Complex Subunit Organization