RPL13A anticorps (AA 63-190)

N° du produit ABIN7142744

Détail du produit anti-RPL13A anticorps

Antigène: RPL13A (Ribosomal Protein L13a (RPL13A))

Épitope: AA 63-190

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RPL13A est non-conjugé

Application: ELISA, Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human 60S ribosomal protein L13a protein (63-190AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RPL13A

Antigène: RPL13A (Ribosomal Protein L13a (RPL13A))

Autre désignation: RPL13A (RPL13A Produits)

Synonymes: anticorps 1810026N22Rik, anticorps Tstap198-7, anticorps tum-antigen, anticorps L13A, anticorps TSTA1, anticorps CG1475, anticorps Dmel\\CG1475, anticorps L13a2, anticorps M(3)83B, anticorps Rp L13A, anticorps anon-EST:Posey125, anticorps anon-EST:fe1A5, anticorps bs25f04.y1, anticorps cg1475, anticorps MGC54018, anticorps GB16111, anticorps hm:zehp0384, anticorps wu:fa95e06, anticorps wu:fb08g07, anticorps wu:fd05d08, anticorps DDBDRAFT_0217704, anticorps DDBDRAFT_0231192, anticorps DDB_0217704, anticorps DDB_0231192, anticorps ribosomal protein L13A, anticorps ribosomal protein L13a, anticorps Ribosomal protein L13A, anticorps ribosomal protein L13a S homeolog, anticorps 60S ribosomal protein L13a, anticorps ribosomal protein 13a, anticorps ribosomal 60S subunit protein L13A, anticorps Ribosomal protein L13a, component of cytosolic 80S ribosome and 60S large subunit, anticorps S60 ribosomal protein L13a, anticorps Rpl13a, anticorps RPL13A, anticorps RpL13A, anticorps rpl13a.S, anticorps rpl13a, anticorps LOC551418, anticorps LOC663151, anticorps RPL13a

Sujet:

Background: Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3\'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex. Involved in methylation of rRNA.

Aliases: RPL13A antibody, 60S ribosomal protein L13a antibody, 23 kDa highly basic protein antibody, Large ribosomal subunit protein uL13 antibody

UniProt: P40429