ACD anticorps (AA 328-497) (HRP)

N° du produit ABIN7143549

L’anticorps Lapin Polyclonal anti-ACD a été validé pour ELISA. Il convient pour détecter ACD dans des échantillons de Humain.

Aperçu rapide pour ACD anticorps (AA 328-497) (HRP) (ABIN7143549)

Antigène: ACD (Adrenocortical Dysplasia Homolog (ACD))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACD est conjugé à/à la HRP

Application: ELISA

Détail du produit anti-ACD anticorps (HRP)

Épitope: AA 328-497

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Adrenocortical dysplasia protein homolog protein (328-497AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ACD

Antigène: ACD (Adrenocortical Dysplasia Homolog (ACD))

Autre désignation: ACD

Sujet:

Background: Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase to telomeres and increasing its processivity. May play a role in organogenesis.

Aliases: Acd antibody, ACD_HUMAN antibody, Adrenocortical dysplasia homolog antibody, Adrenocortical dysplasia protein homolog antibody, PIP1 antibody, POT1 and TIN2 organizing protein antibody, POT1 and TIN2-interacting protein antibody, TIN2 interacting protein 1 antibody, TINT1 antibody, TPP1 antibody

UniProt: Q96AP0

Pathways: Telomere Maintenance