A2ML1 anticorps (AA 625-751)

N° du produit ABIN7143798

Détail du produit anti-A2ML1 anticorps

Antigène: A2ML1 (alpha-2-Macroglobulin-Like 1 (A2ML1))

Épitope: AA 625-751

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp A2ML1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Alpha-2-macroglobulin-like protein 1 protein (625-751AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur A2ML1

Antigène: A2ML1 (alpha-2-Macroglobulin-Like 1 (A2ML1))

Autre désignation: A2ML1 (A2ML1 Produits)

Synonymes: anticorps CPAMD9, anticorps alpha-2-macroglobulin like 1, anticorps A2ML1

Sujet:

Background: Is able to inhibit all four classes of proteinases by a unique \\\'trapping\\\' mechanism. This protein has a peptide stretch, called the \\\'bait region\\\' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase (By similarity). Displays inhibitory activity against chymotrypsin, papain, thermolysin, subtilisin A and, to a lesser extent, elastase but not trypsin. May play an important role during desquamation by inhibiting extracellular proteases.

Aliases: A2ML1 antibody, CPAMD9Alpha-2-macroglobulin-like protein 1 antibody, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 9 antibody

UniProt: A8K2U0