TP53BP2 anticorps (AA 360-600)

N° du produit ABIN7144484

Cet anticorps Lapin Polyclonal détecte spécifiquement TP53BP2 dans WB et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour TP53BP2 anticorps (AA 360-600) (ABIN7144484)

Antigène: TP53BP2 (Tumor Protein P53 Binding Protein 2 (TP53BP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TP53BP2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TP53BP2 anticorps

Épitope: AA 360-600

Fonction: TP53BP2 Antibody

Réactivité croisée: Souris

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Apoptosis-stimulating of p53 protein 2 protein (360-600AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TP53BP2

Antigène: TP53BP2 (Tumor Protein P53 Binding Protein 2 (TP53BP2))

Autre désignation: TP53BP2

Sujet:

Background: Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.

Aliases: 53BP2 antibody, Apoptosis stimulating of p53 protein 2 antibody, Apoptosis stimulating protein of p53 2 antibody, Apoptosis-stimulating of p53 protein 2 antibody, ASPP2 antibody, ASPP2_HUMAN antibody, BBP antibody, Bcl2 binding protein antibody, Bcl2-binding protein antibody, NY REN 51 antigen antibody, p53 binding protein 2 antibody, p53-binding protein 2 antibody, p53BP2 antibody, PPP1R13A antibody, Renal carcinoma antigen NY-REN-51 antibody, Tp53bp2 antibody, Tumor protein p53 binding protein 2 antibody, Tumor suppressor p53 binding protein 2 antibody, Tumor suppressor p53-binding protein 2 antibody

UniProt: Q13625