ALOX12 anticorps (AA 508-658) (FITC)

N° du produit ABIN7144530

Détail du produit anti-ALOX12 anticorps (FITC)

Antigène: ALOX12 (Arachidonate 12-Lipoxygenase (ALOX12))

Épitope: AA 508-658

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALOX12 est conjugé à/à la FITC

Application: Veuillez nous consulter SVP

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Arachidonate 12-lipoxygenase, 12S-type protein (508-658AA)

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ALOX12

Antigène: ALOX12 (Arachidonate 12-Lipoxygenase (ALOX12))

Autre désignation: ALOX12 (ALOX12 Produits)

Synonymes: anticorps 15-LOX-1, anticorps 15LOX-1, anticorps 12-LOX, anticorps 12S-LOX, anticorps LOG12, anticorps ALOX12, anticorps ALOX15, anticorps 9930022G08Rik, anticorps Alox12p, anticorps P-12LO, anticorps 12-LO, anticorps zgc:64120, anticorps wu:fb72a11, anticorps arachidonate 15-lipoxygenase, anticorps arachidonate 12-lipoxygenase, 12S type, anticorps arachidonate 12-lipoxygenase, anticorps arachidonate 12-lipoxygenase, 12S-type, anticorps ALOX15, anticorps ALOX12, anticorps Alox12, anticorps alox12, anticorps LOC100072916

Sujet:

Background: Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Mainly converts arachidonic acid to (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE but can also metabolize linoleic acid. Has a dual activity since it also converts leukotriene A4/LTA4 into both the bioactive lipoxin A4/LXA4 and lipoxin B4/LXB4. Through the production of specific bioactive lipids like (12S)-HPETE it regulates different biological processes including platelet activation. It also probably positively regulates angiogenesis through regulation of the expression of the vascular endothelial growth factor. Plays a role in apoptotic process, promoting the survival of vascular smooth muscle cells for instance. May also play a role in the control of cell migration and proliferation.

Aliases: 12 LOX antibody, 12(S) lipoxygenase antibody, 12-lipoxygenase antibody, 12LO antibody, 12S LOX antibody, 12S-lipoxygenase antibody, 12S-LOX antibody, 12S-type antibody, Alox12 antibody, Arachidonate 12 lipoxygenase antibody, Arachidonate 12 lipoxygenase, 12S type antibody, Arachidonate 12-lipoxygenase antibody, Arachidonate 12-oxidoreductase antibody, Lipoxin synthase 12-LO antibody, LOG12 antibody, LOX12_HUMAN antibody, P-12LO antibody, Platelet 12-LOX antibody, Platelet type lipoxygenase 12 antibody, platelet-type 12-lipoxygenase antibody, Platelet-type lipoxygenase 12 antibody

UniProt: P18054

Pathways: Positive Regulation of Endopeptidase Activity