Aryl Hydrocarbon Receptor anticorps (AA 126-353)
Aperçu rapide pour Aryl Hydrocarbon Receptor anticorps (AA 126-353) (ABIN7144657)
Antigène
Voir toutes Aryl Hydrocarbon Receptor (AHR) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 126-353
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Fonction
- AHR Antibody
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Purification
- Protein G purified
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Pureté
- >95 %
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Immunogène
- Recombinant Human Aryl hydrocarbon receptor protein (126-353AA)
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Aryl Hydrocarbon Receptor (AHR)
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Autre désignation
- AHR
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Sujet
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Background: Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1.
Aliases: Ah receptor antibody, AhR antibody, AHR_HUMAN antibody, Aromatic hydrocarbon receptor antibody, Aryl hydrocarbon receptor antibody, Aryl hydrocarbon receptor precursor antibody, bHLHe76 antibody, Class E basic helix loop helix protein 76 antibody, Class E basic helix-loop-helix protein 76 antibody, HGNC:348 antibody
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UniProt
- P35869
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Pathways
- Regulation of Cell Size
Antigène
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