AHRR anticorps (AA 255-506) (HRP)

N° du produit ABIN7144664

Cet anticorps Lapin Polyclonal détecte spécifiquement AHRR dans ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour AHRR anticorps (AA 255-506) (HRP) (ABIN7144664)

Antigène: AHRR (Aryl-Hydrocarbon Receptor Repressor (AHRR))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AHRR est conjugé à/à la HRP

Application: ELISA

Détail du produit anti-AHRR anticorps (HRP)

Épitope: AA 255-506

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Aryl hydrocarbon receptor repressor protein (255-506AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur AHRR

Antigène: AHRR (Aryl-Hydrocarbon Receptor Repressor (AHRR))

Autre désignation: AHRR

Sujet:

Background: Mediates dioxin toxicity and is involved in regulation of cell growth and differentiation. Represses the transcription activity of AHR by competing with this transcription factor for heterodimer formation with the ARNT and subsequently binding to the xenobiotic response element (XRE) sequence present in the promoter regulatory region of variety of genes. Represses CYP1A1 by binding the XRE sequence and recruiting ANKRA2, HDAC4 and/or HDAC5. Autoregulates its expression by associating with its own XRE site.

Aliases: AHH antibody, AhR repressor antibody, AhRR antibody, AHRR_HUMAN antibody, aryl hydrocarbon hydroxylase regulator antibody, aryl hydrocarbon receptor regulator antibody, Aryl hydrocarbon receptor repressor antibody, Arylhydrocarbon receptor repressor antibody, bHLHe77 antibody, Class E basic helix-loop-helix protein 77 antibody, Dioxin receptor repressor antibody, KIAA1234 antibody, MGC167813 antibody, MGC176630 antibody, OTTHUMP00000221488 antibody, OTTHUMP00000221489 antibody

UniProt: A9YTQ3

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha