BVES anticorps (AA 241-360)

N° du produit ABIN7145640

Détail du produit anti-BVES anticorps

Antigène: BVES (Blood Vessel Epicardial Substance (BVES))

Épitope: AA 241-360

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BVES est non-conjugé

Application: ELISA, Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Blood vessel epicardial substance protein (241-360AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur BVES

Antigène: BVES (Blood Vessel Epicardial Substance (BVES))

Autre désignation: BVES (BVES Produits)

Synonymes: anticorps HBVES, anticorps POP1, anticorps POPDC1, anticorps Pop1, anticorps Popdc1, anticorps mBVES, anticorps Popeye-1, anticorps Xbves, anticorps Xbves-A, anticorps Xpop-1, anticorps Xpop-1-A, anticorps pop-1, anticorps pop1, anticorps pop1-A, anticorps popdc1, anticorps popdc1-A, anticorps zgc:86887, anticorps BVES, anticorps Xpop-1-B, anticorps bves, anticorps pop1-B, anticorps popdc1-B, anticorps hbves, anticorps blood vessel epicardial substance, anticorps blood vessel epicardial substance L homeolog, anticorps blood vessel epicardial substance S homeolog, anticorps BVES, anticorps Bves, anticorps bves.L, anticorps bves, anticorps bves.S

Sujet:

Background: Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells (PubMed:16188940). Plays a role in VAMP3-mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading (By similarity). Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density (PubMed:26642364). Is also a caveolae-associated protein important for the preservation of caveolae structural and functional integrity as well as for heart protection against ischemia injury.

Aliases: Blood vessel epicardial substance antibody, Bves antibody, hBVES antibody, MGC42413 antibody, POP 1 antibody, POP1 antibody, POPD1_HUMAN antibody, POPDC 1 antibody, POPDC1 antibody, Popeye domain containing 1 antibody, Popeye domain containing protein 1 antibody, Popeye domain-containing protein 1 antibody, Popeye protein 1 antibody

UniProt: Q8NE79