CD207 anticorps (AA 229-312)
Aperçu rapide pour CD207 anticorps (AA 229-312) (ABIN7146085)
Antigène
Voir toutes CD207 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 229-312
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Fonction
- CD207 Antibody
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Purification
- Protein G purified
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Pureté
- >95 %
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Immunogène
- Recombinant Human C-type lectin domain family 4 member K protein (229-312AA)
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CD207 (CD207 Molecule, Langerin (CD207))
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Autre désignation
- CD207
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Sujet
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Background: Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs), is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.
Aliases: C type lectin domain family 4 member K antibody, C-type lectin domain family 4 member K antibody, CD 207 antibody, CD207 antibody, CD207 antigen antibody, CD207 antigen, langerin antibody, CD207 Molecule antibody, CLC4K_HUMAN antibody, CLEC 4K antibody, CLEC4K antibody, Langerhans cell specific c type lectin antibody, Langerin antibody, RGD1565913 antibody
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UniProt
- Q9UJ71
Antigène
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