N-Cadherin anticorps (AA 746-906)

N° du produit ABIN7146224

Cet anticorps Lapin Polyclonal détecte spécifiquement N-Cadherin dans WB, IF et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour N-Cadherin anticorps (AA 746-906) (ABIN7146224)

Antigène: N-Cadherin (CDH2) (Cadherin 2 (CDH2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp N-Cadherin est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA

Détail du produit anti-N-Cadherin anticorps

Épitope: AA 746-906

Fonction: CDH2 Antibody

Réactivité croisée: Souris

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Cadherin-2 protein (746-906AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur N-Cadherin

Antigène: N-Cadherin (CDH2) (Cadherin 2 (CDH2))

Autre désignation: CDH2

Sujet:

Background: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity).

Aliases: CADH2_HUMAN antibody, Cadherin 2 antibody, Cadherin 2 N cadherin neuronal antibody, Cadherin 2 type 1 antibody, Cadherin 2 type 1 N cadherin neuronal antibody, Cadherin 2, type 1, N-cadherin (neuronal) antibody, Cadherin-2 antibody, Cadherin2 antibody, Calcium dependent adhesion protein neuronal antibody, CD325 antibody, CD325 antigen antibody, CDH2 antibody, CDHN antibody, CDw325 antibody, CDw325 antigen antibody, N cadherin 1 antibody, N-cadherin antibody, NCAD antibody, Neural cadherin antibody, OTTHUMP00000066304 antibody, OTTHUMP00000067378 antibody

UniProt: P19022

Pathways: Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Synaptic Membrane