CCDC109B anticorps (Regulatory Subunit)

N° du produit ABIN7146318

Détail du produit anti-CCDC109B anticorps

Antigène: CCDC109B (Coiled-Coil Domain Containing 109B (CCDC109B))

Épitope: AA 89-219, Regulatory Subunit

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCDC109B est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Calcium uniporter regulatory subunit MCUb, mitochondrial protein (89-219AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CCDC109B

Antigène: CCDC109B (Coiled-Coil Domain Containing 109B (CCDC109B))

Autre désignation: MCUB (CCDC109B Produits)

Synonymes: anticorps 9030408N13Rik, anticorps mitochondrial calcium uniporter dominant negative beta subunit, anticorps MCUB, anticorps Mcub

Sujet:

Background: Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into the mitochondrion. Does not form functional calcium channels by itself. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.

Aliases: MCUB antibody, CCDC109BCalcium uniporter regulatory subunit MCUb antibody, mitochondrial antibody, MCUb antibody, Coiled-coil domain-containing protein 109B antibody

UniProt: Q9NWR8