CALCOCO1 anticorps (AA 462-691)

N° du produit ABIN7146346

Cet anticorps anti-CALCOCO1 est un anticorps Lapin Polyclonal détectant CALCOCO1 dans WB, IHC et ELISA. Adapté pour Humain.

Aperçu rapide pour CALCOCO1 anticorps (AA 462-691) (ABIN7146346)

Antigène: CALCOCO1 (Calcium Binding and Coiled-Coil Domain 1 (CALCOCO1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CALCOCO1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-CALCOCO1 anticorps

Épitope: AA 462-691

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Calcium-binding and coiled-coil domain-containing protein 1 protein (462-691AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CALCOCO1

Antigène: CALCOCO1 (Calcium Binding and Coiled-Coil Domain 1 (CALCOCO1))

Autre désignation: CALCOCO1

Sujet:

Background: Functions as a coactivator for aryl hydrocarbon and nuclear receptors (NR). Recruited to promoters through its contact with the N-terminal basic helix-loop-helix-Per-Arnt-Sim (PAS) domain of transcription factors or coactivators, such as NCOA2. During ER-activation acts synergistically in combination with other NCOA2-binding proteins, such as EP300, CREBBP and CARM1. Involved in the transcriptional activation of target genes in the Wnt/CTNNB1 pathway. Functions as a secondary coactivator in LEF1-mediated transcriptional activation via its interaction with CTNNB1. Coactivator function for nuclear receptors and LEF1/CTNNB1 involves differential utilization of two different activation regions (By similarity). In association with CCAR1 enhances GATA1- and MED1-mediated transcriptional activation from the gamma-globin promoter during erythroid differentiation of K562 erythroleukemia cells (PubMed:24245781).

Aliases: CALCOCO1 antibody, KIAA1536 antibody, PP13275 antibody, UNQ2436/PRO4996Calcium-binding and coiled-coil domain-containing protein 1 antibody, Calphoglin antibody, Coiled-coil coactivator protein antibody, Sarcoma antigen NY-SAR-3 antibody

UniProt: Q9P1Z2

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Chromatin Binding