COMP anticorps (AA 20-160)

N° du produit ABIN7146850

Cet anticorps anti-COMP est un anticorps Lapin Polyclonal détectant COMP dans WB et ELISA. Adapté pour Humain.

Aperçu rapide pour COMP anticorps (AA 20-160) (ABIN7146850)

Antigène: COMP (Cartilage Oligomeric Matrix Protein (COMP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COMP est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-COMP anticorps

Épitope: AA 20-160

Fonction: COMP Antibody

Réactivité croisée: Souris

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Cartilage oligomeric matrix protein (20-160AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur COMP

Antigène: COMP (Cartilage Oligomeric Matrix Protein (COMP))

Autre désignation: COMP

Sujet:

Background: May play a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. Can mediate the interaction of chondrocytes with the cartilage extracellular matrix through interaction with cell surface integrin receptors. Could play a role in the pathogenesis of osteoarthritis. Potent suppressor of apoptosis in both primary chondrocytes and transformed cells. Suppresses apoptosis by blocking the activation of caspase-3 and by inducing the IAP family of survival proteins (BIRC3, BIRC2, BIRC5 and XIAP). Essential for maintaining a vascular smooth muscle cells (VSMCs) contractile/differentiated phenotype under physiological and pathological stimuli. Maintains this phenotype of VSMCs by interacting with ITGA7.

Aliases: cartilage oligomeric matrix protein (pseudoachondroplasia, epiphyseal dysplasia 1, multiple) antibody, Cartilage oligomeric matrix protein antibody, Cartilage oligomeric matrix protein precursor antibody, COMP antibody, COMP_HUMAN antibody, EDM 1 antibody, EDM1 antibody, EPD 1 antibody, EPD1 antibody, Epiphyseal dysplasia 1 antibody, Epiphyseal dysplasia 1 multiple antibody, Epiphyseal dysplasia multiple 1 antibody, MED antibody, MGC13181 antibody, MGC149768 antibody, PSACH antibody, pseudoachondroplasia (epiphyseal dysplasia 1, multiple) antibody, Pseudoachondroplasia antibody, THBS 5 antibody, THBS5 antibody, Thrombospondin 5 antibody, Thrombospondin-5 antibody, Thrombospondin5 antibody, TSP5 antibody

UniProt: P49747