CNOT2 anticorps (AA 1-335) (FITC)
Aperçu rapide pour CNOT2 anticorps (AA 1-335) (FITC) (ABIN7147099)
Antigène
Voir toutes CNOT2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-335
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Réactivité croisée
- Humain
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Purification
- >95%, Protein G purified
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Immunogène
- Recombinant Human CCR4-NOT transcription complex subunit 2 protein (1-335AA)
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Isotype
- IgG
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CNOT2 (CCR4-NOT Transcription Complex, Subunit 2 (CNOT2))
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Autre désignation
- CNOT2
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Sujet
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Background: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for the CCR4-NOT complex structural integrity. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation, the repressive function may specificly involve the N-Cor repressor complex containing HDAC3, NCOR1 and NCOR2. Involved in the maintenance of emryonic stem (ES) cell identity.
Aliases: CCR4 associated factor 2 antibody, CCR4 NOT transcription complex subunit 2 antibody, CCR4-associated factor 2 antibody, CCR4-NOT transcription complex subunit 2 antibody, CDC36 antibody, CNOT2 antibody, CNOT2_HUMAN antibody, HSPC131 antibody, MSTP046 antibody, Negative regulator of transcription 2 antibody, NOT2 (negative regulator of transcription 2 yeast) homolog antibody, NOT2 antibody, NOT2H antibody
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UniProt
- Q9NZN8
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance
Antigène
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