CNOT3 anticorps (AA 257-395) (Biotin)

N° du produit ABIN7147102

Cet anticorps anti-CNOT3 est un anticorps Lapin Polyclonal détectant CNOT3 dans ELISA. Adapté pour Humain.

Aperçu rapide pour CNOT3 anticorps (AA 257-395) (Biotin) (ABIN7147102)

Antigène: CNOT3 (CCR4-NOT Transcription Complex, Subunit 3 (CNOT3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CNOT3 est conjugé à/à la Biotin

Application: ELISA

Détail du produit anti-CNOT3 anticorps (Biotin)

Épitope: AA 257-395

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human CCR4-NOT transcription complex subunit 3 protein (257-395AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CNOT3

Antigène: CNOT3 (CCR4-NOT Transcription Complex, Subunit 3 (CNOT3))

Autre désignation: CNOT3

Sujet:

Background: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in metabolic regulation, may be involved in recruitment of the CCR4-NOT complex to deadenylation target mRNAs involved in energy metabolism. Involved in mitotic progression and regulation of the spindle assembly checkpoint by regulating the stability of MAD1L1 mRNA. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation, the repressive function may involve histone deacetylases. Involved in the maintenance of emryonic stem (ES) cell identity.

Aliases: CCR4 associated factor 3 antibody, CCR4-associated factor 3 antibody, CCR4-NOT transcription complex subunit 3 antibody, CNOT3 antibody, CNOT3_HUMAN antibody, KIAA0691 antibody, LENG2 antibody, Leukocyte receptor cluster member 2 antibody, negative regulator of transcription 3, S. cerevisiae, homolog of antibody, NOT3 (negative regulator of transcription 3, yeast) homolog antibody, NOT3 antibody, NOT3H antibody

UniProt: O75175

Pathways: Stem Cell Maintenance