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CD31 anticorps (AA 28-315)

Name: CD31 anticorps (AA 28-315)
Brand: antibodies-online
SKU: ABIN7147154
Price: 415 EUR
Availability: InStock

PECAM1 Reactivité: Humain FACS, WB, IHC, IF, ELISA Hôte: Souris Monoclonal 9E6E12 unconjugated

Western Blot Positive WB detected in: Jurkat whole cell lysate, THP-1 whole cell lysate, Raji whole cell lysate All lanes: CD31 antibody at 2. (CD31 anticorps (AA 28-315))

IHC image of ABIN7147154 diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. (CD31 anticorps (AA 28-315))

IHC

IHC image of ABIN7147154 diluted at 1:100 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. (CD31 anticorps (AA 28-315))

IHC

IHC image of ABIN7147154 diluted at 1:100 and staining in paraffin-embedded human lung cancer performed on a Leica BondTM system. (CD31 anticorps (AA 28-315))

9 images

N° du produit ABIN7147154

Fiche de données

Antigène Voir toutes CD31 (PECAM1) Anticorps

CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
Épitope
18

16

16

12

8

8

7

6

5

4

4

4

4

3

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 28-315
Reactivité
274

142

72

59

42

28

22

18

7

4

4

3

2

1

1

1
Humain
Hôte
158

148

48

7

3

2
Souris
Anticorps secondaires appropriés
Clonalité
232

133

1
Monoclonal
Conjugué
156

33

33

24

11

8

7

7

5

5

5

5

5

5

5

5

5

5

5

3

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1
Cet anticorp CD31 est non-conjugé
Application
227

185

96

87

62

38

36

33

26

26

22

15

13

9

6

5

4

3

3

3

2

2

2

2

1

1

1

1

1
Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Réactivité croisée

Humain

Purification

Protein G purified

Immunogène

Recombinant Human CD31 protein (28-315AA)

Clone

9E6E12

Isotype

IgG2a

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anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) (AA 625-738) antibody
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anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) (AA 29-738) antibody
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Indications d'application

Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:500, IF:1:50-1:200,

Restrictions

For Research Use only
Format

Liquid

Buffer

Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur

ProClin

Précaution d'utilisation

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

-20 °C,-80 °C

Stockage commentaire

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Antigène

CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Autre désignation

CD31 (PECAM1 Produits)

Synonymes

anticorps CD31, anticorps CD31/EndoCAM, anticorps GPIIA', anticorps PECA1, anticorps PECAM-1, anticorps endoCAM, anticorps C85791, anticorps Cd31, anticorps Pecam, anticorps platelet/endothelial cell adhesion molecule 1, anticorps platelet and endothelial cell adhesion molecule 1, anticorps pecam1, anticorps PECAM1, anticorps Pecam1

Sujet

Background: Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions (PubMed:19342684, PubMed:17580308). Tyr-690 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes (PubMed:19342684). Heterophilic interaction with CD177 plays a role in transendothelial migration of neutrophils (PubMed:17580308). Homophilic ligation of PECAM1 prevents macrophage-mediated phagocytosis of neighboring viable leukocytes by transmitting a detachment signal (PubMed:12110892). Promotes macrophage-mediated phagocytosis of apoptotic leukocytes by tethering them to the phagocytic cells, PECAM1-mediated detachment signal appears to be disabled in apoptotic leukocytes (PubMed:12110892). Modulates bradykinin receptor BDKRB2 activation (PubMed:18672896). Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in endothelial cells (PubMed:18672896). Induces susceptibility to atherosclerosis (By similarity).
Aliases: Platelet endothelial cell adhesion molecule, PECAM-1, EndoCAM, GPIIA', PECA1, CD31, PECAM1

UniProt

P16284

Pathways

Regulation of Actin Filament Polymerization