CIDEA anticorps (AA 1-51)

N° du produit ABIN7147273

Cet anticorps anti-CIDEA est un anticorps Lapin Polyclonal détectant CIDEA dans WB, ELISA, IHC et IF. Adapté pour Humain.

Aperçu rapide pour CIDEA anticorps (AA 1-51) (ABIN7147273)

Antigène: CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CIDEA est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-CIDEA anticorps

Épitope: AA 1-51

Réactivité croisée: Humain, Souris

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Cell death activator CIDE-A protein (1-51AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CIDEA

Antigène: CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

Autre désignation: CIDEA

Sujet:

Background: Acts as a CEBPB coactivator in mammary epithelial cells to control the expression of a subset of CEBPB downstream target genes, including ID2, IGF1, PRLR, SOCS1, SOCS3, XDH, but not casein. By interacting with CEBPB, strengthens the association of CEBPB with the XDH promoter, increases histone acetylation and dissociates HDAC1 from the promoter (By similarity). Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair and occurs at a lower rate than that promoted by CIDEC. When overexpressed, induces apoptosis. The physiological significance of its role in apoptosis is unclear.

Aliases: CIDEACell death activator CIDE-A antibody, Cell death-inducing DFFA-like effector A antibody

UniProt: O60543