CHMP5 anticorps (AA 1-219) (HRP)

N° du produit ABIN7147532

Cet anticorps Lapin Polyclonal détecte spécifiquement CHMP5 dans ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour CHMP5 anticorps (AA 1-219) (HRP) (ABIN7147532)

Antigène: CHMP5 (Charged Multivesicular Body Protein 5 (CHMP5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHMP5 est conjugé à/à la HRP

Application: ELISA

Détail du produit anti-CHMP5 anticorps (HRP)

Épitope: AA 1-219

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Charged multivesicular body protein 5 protein (1-219AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CHMP5

Antigène: CHMP5 (Charged Multivesicular Body Protein 5 (CHMP5))

Autre désignation: CHMP5

Sujet:

Background: Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in HIV-1 p6- and p9-dependent virus release.

Aliases: apoptosis-related protein PNAS-2 antibody, C9orf83 antibody, CGI 34 antibody, Charged multivesicular body protein 5 antibody, CHMP 5 antibody, CHMP family, member 5 antibody, chmp5 antibody, CHMP5_HUMAN antibody, Chromatin modifying protein 5 antibody, Chromatin-modifying protein 5 antibody, Chromosome 9 open reading frame 83 antibody, HGNC:26942 antibody, HSPC177 antibody, hVps60 antibody, PNAS 2 antibody, SNF7 domain containing protein 2 antibody, SNF7 domain-containing protein 2 antibody, SNF7DC2 antibody, Vacuolar protein sorting 60 antibody, Vacuolar protein sorting-associated protein 60 antibody, Vps60 antibody

UniProt: Q9NZZ3