CHMP6 anticorps (AA 2-201) (HRP)

N° du produit ABIN7147536

L’anticorps Lapin Polyclonal anti-CHMP6 a été validé pour ELISA. Il convient pour détecter CHMP6 dans des échantillons de Humain.

Aperçu rapide pour CHMP6 anticorps (AA 2-201) (HRP) (ABIN7147536)

Antigène: CHMP6 (Charged Multivesicular Body Protein 6 (CHMP6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHMP6 est conjugé à/à la HRP

Application: ELISA

Détail du produit anti-CHMP6 anticorps (HRP)

Épitope: AA 2-201

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Charged multivesicular body protein 6 protein (2-201AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CHMP6

Antigène: CHMP6 (Charged Multivesicular Body Protein 6 (CHMP6))

Autre désignation: CHMP6

Sujet:

Background: Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. In the ESCRT-III complex, it probably serves as an acceptor for the ESCRT-II complex on endosomal membranes.

Aliases: Charged multivesicular body protein 6 antibody, chmp6 antibody, CHMP6_HUMAN antibody, Chromatin modifying protein 6 antibody, Chromatin-modifying protein 6 antibody, FLJ11749 antibody, hVps 20 antibody, hVps20 antibody, novel SNF7 protein antibody, OTTMUSP00000004363 antibody, RGD1565325 antibody, RP24 225K18.4 antibody, Vacuolar protein sorting associated protein 20 antibody, Vacuolar protein sorting-associated protein 20 antibody, Vps 20 antibody, Vps20 antibody

UniProt: Q96FZ7