INO80 anticorps (AA 1365-1495)

N° du produit ABIN7147693

Cet anticorps anti-INO80 est un anticorps Lapin Polyclonal détectant INO80 dans ELISA, WB et IF. Adapté pour Humain.

Aperçu rapide pour INO80 anticorps (AA 1365-1495) (ABIN7147693)

Antigène: INO80 (INO80 Homolog (INO80))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp INO80 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-INO80 anticorps

Épitope: AA 1365-1495

Fonction: INO80 Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Chromatin-remodeling ATPase INO80 protein (1365-1495AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur INO80

Antigène: INO80 (INO80 Homolog (INO80))

Autre désignation: INO80

Sujet:

Background: ATPase component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and DNA repair (PubMed:16230350, PubMed:16298340, PubMed:17721549, PubMed:20855601, PubMed:20237820). Binds DNA (PubMed:16298340, PubMed:21303910). As part of the INO80 complex, remodels chromatin by shifting nucleosomes (PubMed:16230350, PubMed:21303910). Regulates transcription upon recruitment by YY1 to YY1-activated genes, where it acts as an essential coactivator (PubMed:17721549). Involved in UV-damage excision DNA repair (PubMed:20855601). The contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation (PubMed:20687897). Involved in DNA replication (PubMed:20237820). Required for microtubule assembly during mitosis thereby regulating chromosome segregation cycle (PubMed:20237820).

Aliases: DNA helicase INO80 antibody, hINO80 antibody, homolog of yeast INO80 antibody, INO80 antibody, INO80 complex subunit A antibody, INO80 homolog antibody, INO80_HUMAN antibody, INO80A antibody, INOC1 antibody, KIAA1259 antibody, Putative DNA helicase INO80 complex homolog 1 antibody

UniProt: Q9ULG1

Pathways: Positive Regulation of Response to DNA Damage Stimulus