CRTC2 anticorps (AA 180-372) (Biotin)

N° du produit ABIN7148680

Cet anticorps anti-CRTC2 est un anticorps Lapin Polyclonal détectant CRTC2 dans ELISA. Adapté pour Humain.

Aperçu rapide pour CRTC2 anticorps (AA 180-372) (Biotin) (ABIN7148680)

Antigène: CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRTC2 est conjugé à/à la Biotin

Application: ELISA

Détail du produit anti-CRTC2 anticorps (Biotin)

Épitope: AA 180-372

Fonction: CRTC2 Antibody, Biotin conjugated

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human CREB-regulated transcription coactivator 2 protein (180-372AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CRTC2

Antigène: CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

Autre désignation: CRTC2

Sujet:

Background: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 \'Ser-133\' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).

Aliases: CREB regulated transcription coactivator 2 antibody, CREB-regulated transcription coactivator 2 antibody, CRTC2 antibody, CRTC2_HUMAN antibody, RP11-422P24.6 antibody, TORC-2 antibody, torc2 antibody, Transducer of CREB protein 2 antibody, Transducer of regulated cAMP response element-binding protein antibody, Transducer of regulated cAMP response element-binding protein (CREB) 2 antibody, Transducer of regulated cAMP response element-binding protein 2 antibody, Transducer of regulated CREB protein 2 antibody

UniProt: Q53ET0

Pathways: AMPK Signaling, Carbohydrate Homeostasis