Cullin 5 anticorps (AA 1-300)

N° du produit ABIN7148758

Cet anticorps anti-Cullin 5 est un anticorps Lapin Polyclonal détectant Cullin 5 dans ELISA et IHC. Adapté pour Humain.

Aperçu rapide pour Cullin 5 anticorps (AA 1-300) (ABIN7148758)

Antigène: Cullin 5 (CUL5)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cullin 5 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-Cullin 5 anticorps

Épitope: AA 1-300

Fonction: CUL5 Antibody

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Cullin-5 protein (1-300AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Cullin 5

Antigène: Cullin 5 (CUL5)

Autre désignation: CUL5

Sujet:

Background: Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor.

Aliases: CUL 5 antibody, CUL-5 antibody, CUL5 antibody, CUL5_HUMAN antibody, Cullin 5 antibody, Cullin-5 (vasopressin-activated calcium-mobilizing receptor-1) antibody, Cullin-5 antibody, Cullin5 antibody, VACM 1 antibody, VACM-1 antibody, VACM1 antibody, Vasopressin activated calcium mobilizing receptor 1 antibody, Vasopressin activated calcium mobilizing receptor antibody, Vasopressin-activated calcium-mobilizing receptor 1 antibody, Vasopressin-activated calcium-mobilizing receptor-1 antibody

UniProt: Q93034

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development